Platelet Reactivity
نویسندگان
چکیده
منابع مشابه
Flavanols and Platelet Reactivity
Platelet activity and platelet-endothelial cell interactions are important in the acute development of thrombosis, as well as in the pathogenesis of cardiovascular disease. An increasing number of foods have been reported to have platelet-inhibitory actions, and research with a number of flavanol-rich foods, including, grape juice, cocoa and chocolate, suggests that these foods may provide some...
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BACKGROUND Gestational thrombocytopenia is more likely to occur in twin than singleton pregnancies. However, it is unclear whether platelets are more reactive in twin than singleton pregnancies. METHODS Changes in spontaneous platelet aggregation and concomitant fall in platelet count were examined over 90min after blood sampling in 171 and 52 citrated whole blood (CWB) samples from 59 and 17...
متن کاملAtrial fibrillation and platelet reactivity.
BACKGROUND The impact of atrial fibrillation (AF) upon platelet reactivity has not been investigated. METHODS Subjects were 33 individuals with AF who consented to elective electrical cardioversion (ECV) immediately before ECV determination of surface-bound fibrinogen after stimulation i.e. platelet reactivity was carried out. A flow cytometer was employed. ADP (1.7 and 8.5 μmol/L) and a thro...
متن کاملMicroRNA Biomarkers and Platelet Reactivity
Platelets play a key role in hemostasis, initiating and propagating thrombosis. Dysregulation and inappropriate activation of platelets underpin a wide range of important diseases, including stroke and myocardial infarction, whereas impairment of platelet function results in bleeding disorders. Platelets are anucleate and were previously considered to be simple cytoplasmic fragments of megakary...
متن کاملPlatelet receptor proteolysis: a mechanism for downregulating platelet reactivity.
The platelet plasma membrane is literally at the cutting-edge of recent research into proteolytic regulation of the function and surface expression of platelet receptors, revealing new mechanisms for how the thrombotic propensity of platelets is controlled in health and disease. Extracellular proteolysis of receptors irreversibly inactivates receptor-mediated adhesion and signaling, as well as ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2017
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2016.07.791